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Medications that inhibit CYP2D6 action, for example paroxetine and quinidine, may well induce decreased clearance of oxycodone which could lead on to an increase in oxycodone plasma concentrations. Concurrent administration of quinidine resulted in an increase in oxycodone Cmax by 11%, AUC by thirteen%, and t½ elim.Just like all opioid preparation

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